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Melkersson-Rosenthal Syndrome is a rare, idiopathic non caseating granulomatous condition characterized by a classic triad of recurrent facial/labial swelling, fissured tongue and recurrent facial palsy. Different therapeutic regimens have been attempted but with limited success. We report a 47-year-old woman with recurrent lip swelling, lingua plicata and recurrent peripheral facial nerve palsy on both sides who benefited from a short course of oral steroids. Literature on various aspects of the disease is reviewed and discussed.