Annals of Indian Academy of Neurology
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Year : 2007  |  Volume : 10  |  Issue : 1  |  Page : 52-54

Reversible paraneoplastic encephalomyelitis as the presenting feature of ovarian teratoma: A clinicopathological correlate

1 Department of Medical Oncology, Nizam's Institute of Medical Sciences, Hyderabad, India
2 Department of Pathology, Nizam's Institute of Medical Sciences, Hyderabad, India
3 Department of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, India

Correspondence Address:
Senthil J Rajappa
Dept. of Medical Oncology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad - 500 016
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-2327.31487

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Paraneoplastic encephalomyelitis (PEM) is a well-characterized neurological syndrome. Its association with ovarian teratoma is rare. A young lady presented with features suggestive of encephalomyelitis with predominant cerebellar syndrome. Magnetic resonance imaging brain was normal. Cerebrospinal fluid showed lymphocytic pleocytosis. Computerized tomography scan of the pelvis revealed a complex left ovarian cyst. With a clinical diagnosis of PEM she underwent a left salpingo-oopherectomy. This was followed by total recovery of the PEM in two weeks. The histopathology revealed immature teratoma. The interesting feature was the clinicopathological correlation between the finding of fetal cerebellar tissue in the tumor and the PEM with predominant cerebellar features.

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