Annals of Indian Academy of Neurology
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Year : 2014  |  Volume : 17  |  Issue : 3  |  Page : 349-351

Relapsing Anti-NMDAR Encephalitis after a gap of eight years in a girl from North-East India

Department of Neurology, Gauhati Medical College and Hospital, Guwahati, Assam, India

Correspondence Address:
Suvorit Bhowmick
House Number 6, Third Floor, Rupali Path, Roop Nagar Road, Guwahati - 781 032, Assam
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-2327.138526

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It has been just 7 years since the discovery of anti-NMDAR encephalitis as distinct immune-mediated encephalitis and we have such cases being reported from our country. Herein, we describe a case of a 13-year-old girl who had relapsing encephalitis consisting of multiple types of difficult-to-control seizures, abnormal behavior, language disintegration, memory loss and abnormal movements eight years after the first clinical attack. In 2005, when she was 5 yearsold, anti-NMDAR encephalitis was not yet discovered and she was provisionally diagnosed as a case of viral encephalitis. During her second attack in 2013, antibodies against NMDAR were demonstrated by immunofluoresence in serum (1:10). This is the first report from our country of a case of relapsing anti-NMDAR encephalitis of such a long duration, successfully treated by immunotherapy.

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