Annals of Indian Academy of Neurology
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CASE REPORT
Year : 2014  |  Volume : 17  |  Issue : 3  |  Page : 352-354

Relapsing Guillain-Barre syndrome in pregnancy and postpartum


1 Department of Neurology, Apollo Specialty Hospital, Madurai, Tamil Nadu, India
2 Department of Endocrinology, Apollo Specialty Hospital, Madurai, Tamil Nadu, India

Correspondence Address:
S Meenakshi-Sundaram
Department of Neurology, Apollo Specialty Hospital, Madurai, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.138527

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Guillain-Barre syndrome (GBS) rarely complicates pregnancy, but can be associated with high maternal and perinatal morbidity if not properly identified and treated. A high index of suspicion, supportive measures, access to intensive care unit and intravenous immunoglobulin (IVIG) therapy are cornerstones of management in GBS complicating pregnancy. Neurologists and Obstetricians should be aware of the risks of relapsing GBS in the immediate postpartum period. Surgery and anesthesia may be triggers for relapse in association with an overall increase in pro-inflammatory cytokines in the postpartum period. We report a unique case of GBS complicating pregnancy in the third trimester followed by a relapse in the postpartum period. She made a good recovery with supportive measures and a repeat course of IVIG during the relapse.


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