Annals of Indian Academy of Neurology
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Year : 2016  |  Volume : 19  |  Issue : 4  |  Page : 478-481

Clinical correlates of leukoaraiosis: A study of 175 patients

1 Consultant Neurologist, Pune, Maharashtra, India
2 Consultant Radiologist, Pune, Maharashtra, India
3 Resident at Ruby Hall Clinic, Pune, Maharashtra, India
4 Assistant Professor, Bharati Medical College, Pune, Maharashtra, India
5 Consultant Neurologist, Columbia Asia Hospital, Pune, Maharashtra, India

Correspondence Address:
Rustom S Wadia
Director Neurological Services, Ruby Hall Clinic, Pune, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-2327.194425

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Background: In India, the correlates of leukoaraiosis (LA) have not been widely reported. This study was designed to investigate the factors which correlate with LA. Materials and Methods: We included patients with LA who consented for the study and graded their severity on the basis of Fazekas scale. We excluded patients with LA who did not consent/cooperate for the study as also patients with other white matter changes which mimic LA. Results: LA is a common and under-rated cause of disability. Presentations include cognitive decline, gait disturbance, dysarthria, bladder/bowel sphincter disturbances, and increased risk of stroke. The comorbidities include hyperhomocysteinemia, hypertension, dyslipidemia, tobacco use, ischemic heart disease, previous stroke, atrial fibrillation, chronic renal failure, and bariatric surgery.

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