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Year : 2020  |  Volume : 23  |  Issue : 4  |  Page : 577

Parkinson's Disease in India: From clinic to bench

Department of Neurology, Parkinson's Disease and Movement Disorders Centre, USA Parkinson Foundation International Center of Excellence, National Neuroscience Institute, Singapore

Date of Submission25-Feb-2020
Date of Decision14-Apr-2020
Date of Acceptance28-Feb-2020
Date of Web Publication21-Aug-2020

Correspondence Address:
Louis C S. Tan
Department of Neurology, National Neuroscience Institute, 308433
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/aian.AIAN_119_20

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How to cite this article:
S. Tan LC, Kohat AK. Parkinson's Disease in India: From clinic to bench. Ann Indian Acad Neurol 2020;23:577

How to cite this URL:
S. Tan LC, Kohat AK. Parkinson's Disease in India: From clinic to bench. Ann Indian Acad Neurol [serial online] 2020 [cited 2021 Sep 22];23:577. Available from:

Editors : Madhuri Behari, SPGorthi

Published by : Manipal Universal Press

Year of publication : 2019

Pages : 288

Price : 1500 INR

ISBN-10 : 978-93-82460-93-0

Parkinson's disease (PD) has always fascinated clinicians with its clinicopathological diversities. Since the description of “Shaking Palsy,” 200 years ago, there has been tremendous development in the field of PD. “Parkinson's disease in India: from clinic to bench” is an endeavor to summarize the epidemiology, pathophysiology, clinical dimensions, and latest trends in the management of PD.

This hardcover book is contributed by 36 authors who are experts in their respective disciplines. The book comprises 27 chapters and each chapter is devoted to a distinct aspect of PD.

The initial chapters present an excellent overview of the epidemiology of the PD in India with an outstanding review of literature. The synopsis on the genetics of PD demonstrates the evolving frontiers in genetic research in the country. The next chapter provides a comprehensive elaboration of the various subclasses of biomarkers in PD. Next, is an amazing, concise chapter on the contribution of computers in classifying PD. Various models have already been proposed and this chapter provides valuable ideas as to how technology may be applied to benefit modern-day clinics and research.

Further chapters explore the clinical dimensions of PD. There are dedicated chapters for memory and cognition, autonomic disturbances, gait, balance, speech, olfactory disturbance, and other motor and non-motor symptoms that affect PD. The rationale and the evidence for the management of PD are effectively illustrated. Stem cell therapy in PD is a new hot potato topic. Regenerating the midbrain dopaminergic neurons from pluripotent stem cells are already being performed in a few trials. The chapter on stem cell summarizes all the latest trends in stem cell research. Quality of life (QOL) and caregivers' burden are essential aspects of the PD. Longer disease duration is associated with higher caregivers' burden and a poorer QOL. This scenario is further worsened in developing nations.

Finally, the Editors included a chapter on the knowledge, attitude, and perception in PD. It is essential to fill the knowledge and information gap amongst caregivers, patients, and physicians so that each group may be empowered to better manage the disease.

This book is a wonderful work and labor of love put together by Professors Behari and Gorthi who have dedicated their lives to teach and mentor many generations of neurologists in India and the region. The major strengths of this book are the competent authors and its much esteemed and experienced Editors who have kept the style of the book simple and intelligible. This book is highly recommended for all practicing neurologists and residents to keep abreast of the latest developments in PD.


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