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Intracerebral hemorrhage and SARS-CoV-2: Association or causation
Ayush Agarwal, Venugopalan Y Vishnu, Deepti Vibha, Rohit Bhatia, Anu Gupta, Animesh Das, MV Padma Srivastava
Department of Neurology, AIIMS, New Delhi, India
Correspondence Address:
MV Padma Srivastava,
Department of Neurology, AIIMS, New Delhi
India
 Source of Support: None, Conflict of Interest: None DOI: 10.4103/aian.AIAN_362_20
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Background: Recent respiratory infection including SARS-CoV-2 is an independent risk factor for acute cerebrovascular disease. Purpose: There have been reports linking haemorrhagic strokes to SARS-CoV-2 infection during this pandemic, which lead us to evaluate if SARS-CoV-2 infection could be associated with increased risk of intracerebral haemorrhage (ICH). Methods: A retrospective observational study evaluating all stroke cases admitted in our centre in the past one month. Results: More than half (56%) had ICH, compared to 22% last year. Two patients with ICH were SARS-CoV-2 positive and they had no or mild respiratory symptoms and had higher occurrence of renal dysfunction. Conclusion: There could be possible association between ICH and SARS-CoV-2 infections. However, a prospective study with larger sample size is needed to elucidate the pathogenesis.
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