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Role of vitamin D in cerebrovascular disease
Subhash Kaul, Jayasree Manikinda
Department of Neurology, Krishna Institute of Medical Sciences, Secunderabad, Telangana, India
Correspondence Address:
Subhash Kaul,
Department of Neurology, Krishna Institute of Medical Sciences Hospital, Ministers Road, Secunderabad - 500 003, Telangana
India
 Source of Support: None, Conflict of Interest: None DOI: 10.4103/aian.AIAN_928_20
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Introduction: Vitamin D deficiency is now a well-recognized public health problem affecting almost every second person throughout the world. Recent evidence from many population-based studies has indicated that a poor vitamin D status is a predictor of future strokes. Materials and Methods: We reviewed recent studies on 25-hydroxyvitamin D [25(OH)D] and symptomatic ischemic stroke. A graded increase in the risk of symptomatic ischemic stroke with decreasing levels of plasma 25(OH)D has been found in most of the studies. Vitamin D also has a role in the poststroke period where its deficiency may hinder the rehabilitation process. Conclusions: After reviewing current literature on the subject, we conclude that there are some data to suggest the role of vitamin D in patients with stroke but it cannot be concluded as a risk factor for stroke. Larger population-based studies are needed to confirm the causative role of vitamin D in stroke.
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