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Annals of Indian Academy of Neurology
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AIAN REVIEW
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A narrative review study on the effects of obesity and bariatric surgery on multiple sclerosis


1 MS Fellowship, Department of Neurology, Tehran University of Medical Sciences, Tehran, Iran
2 Nephrologist, Department of Internal Medicine, Tehran University of Medical Sciences, Tehran, Iran
3 Associate Professor of General Surgery (Fellowship of Minimally Invasive Surgery), Department of Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4 Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
5 General Surgeon (Fellowship of Minimally Invasive Surgery), Department of Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6 Department of pharmacology, Bam University of Medical Sciences, Bam, Iran

Correspondence Address:
Zohreh Abna,
Department of Neurology, Sina Hospital, Tehran
Iran
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/aian.AIAN_235_21

Obesity is a major public health concern and should be considered in autoimmune inflammatory disorders, such as multiple sclerosis (MS). In these patients, obesity leads to increasing comorbidities as well as reduced quality of life. Obesity causes an inflammatory state in the body, especially in adolescents; obesity has a role in the pathogenesis of MS. Hence, it is identified as a lifestyle modifiable risk factor for MS disease. Among various treatments for obesity, bariatric surgery has been widely used. Although few studies have been performed on bariatric surgery in MS patients, in this review, we present the existing data regarding the effects of obesity on the MS course and evaluate the outcomes of bariatric surgery among this population.


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    -  Abna Z
    -  Fazeli SA
    -  Mirhashemi S
    -  Mirzaei K
    -  Emami F
    -  Jamili S
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