Annals of Indian Academy of Neurology
CASE REPORT
Year
: 2014  |  Volume : 17  |  Issue : 2  |  Page : 227--230

Primary diffuse leptomeningeal gliomatosis: An autopsy case report


Shaik Afshan Jabeen1, Arikapadu Haritha Chowdary1, Rukmini Mridula Kandadai1, Megha S. Uppin2, Angamattu Kanikannan Meena1, Rupam Borgohain1, Challa Sundaram2 
1 Department of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, India
2 Department of Pathology, Nizam's Institute of Medical Sciences, Hyderabad, India

Correspondence Address:
Shaik Afshan Jabeen
Department of Neurology, Nizam«SQ»s Institute of Medical Sciences, Punagutta, Hyderabad
India

Primary diffuse leptomeningeal gliomatosis (PDLG) is a rare condition, characterized by infiltration of the meninges by glial cells without evidence of the primary tumor in the brain or spinal cord parenchyma. Glioma arising primarily from the leptomeninges is extremely rare and often diagnosed only in post mortem examination and the diagnosis may be missed in meningeal biopsy. We describe a young female who presented with symptoms of raised intracranial pressure with imaging evidence of diffuse leptomeningeal enhancement in whom autopsy confirmed the diagnosis of PDLG. Our case illustrates the diagnostic difficulties in making the pre-mortem diagnosis even with multiple cerebrospinal fluid cytologies and leptomeningeal biopsy.


How to cite this article:
Jabeen SA, Chowdary AH, Kandadai RM, Uppin MS, Meena AK, Borgohain R, Sundaram C. Primary diffuse leptomeningeal gliomatosis: An autopsy case report.Ann Indian Acad Neurol 2014;17:227-230


How to cite this URL:
Jabeen SA, Chowdary AH, Kandadai RM, Uppin MS, Meena AK, Borgohain R, Sundaram C. Primary diffuse leptomeningeal gliomatosis: An autopsy case report. Ann Indian Acad Neurol [serial online] 2014 [cited 2022 Jan 29 ];17:227-230
Available from: https://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=2;spage=227;epage=230;aulast=Jabeen;type=0