Annals of Indian Academy of Neurology
CASE REPORT
Year
: 2016  |  Volume : 19  |  Issue : 3  |  Page : 388--391

Hemi-meningitis with hemophagocytic lymphohistiocytosis


Ozan Kocak1, Coskun Yarar1, Sevgi Yimenicioğlu2, Arzu Ekici3, Özcan Bör4 
1 Department of Pediatric Neurology, Eskisehir Osmangazi University Hospital, Eskisehir, Turkey
2 Department of Pediatric Neurology, Eskişehir State Hospital, Eskisehir, Turkey
3 Department of Pediatric Neurology, Bursa Sevket Yilmaz Education and Research Hospital, Bursa, Turkey
4 Department of Pediatric Hematology, Eskisehir Osmangazi University Hospital, Eskisehir, Turkey

Correspondence Address:
Ozan Kocak
Department of Pediatric Neurology, Eskisehir Osmangazi University Hospital, Meselik, Eskisehir
Turkey

Hemophagocytic lymphohistiocytosis (HLH) is a rare lymphoproliferative disorder. HLH may occur as a complication of Epstein-Barr virus (EBV), particularly in patients with immunodeficiencies. Herein, we describe a 16-year-old girl with neurological complications associated EBV-induced HLH. Her cerebral magnetic resonance imaging (MRI) showed contrast-enhanced axial T1-weighted images with enhancement of meningeal surface in the right hemisphere that was consistent with right hemi-meningitis. Hydrocephalus, dilated subdural spaces, delayed myelination, edema, diffuse parenchymal atrophy, calcifications, diffuse/patchy white matter abnormalities have all been previously described with HLH. To the best of our knowledge, this is the first case of hemi-meningitis associated with HLH. We suggest that clinicians should consider HLH with vascular disorders when they determine unilateral meningitis on a brain MRI.


How to cite this article:
Kocak O, Yarar C, Yimenicioğlu S, Ekici A, Bör &. Hemi-meningitis with hemophagocytic lymphohistiocytosis.Ann Indian Acad Neurol 2016;19:388-391


How to cite this URL:
Kocak O, Yarar C, Yimenicioğlu S, Ekici A, Bör &. Hemi-meningitis with hemophagocytic lymphohistiocytosis. Ann Indian Acad Neurol [serial online] 2016 [cited 2021 Apr 19 ];19:388-391
Available from: https://www.annalsofian.org/article.asp?issn=0972-2327;year=2016;volume=19;issue=3;spage=388;epage=391;aulast=Kocak;type=0