Annals of Indian Academy of Neurology
ORIGINAL ARTICLE
Year
: 2016  |  Volume : 19  |  Issue : 4  |  Page : 495--498

The clinical significance of brain microbleeds in patients with Alzheimer«SQ»s disease: Preliminary study


Jae-Hyeok Heo, Dong-Gyu Im, Seung-Hyeon Lee, Jin-Young Ahn 
 Department of Neurology, Seoul Medical Center, Chungrang-gu, Seoul 131-130, Korea

Correspondence Address:
Jin-Young Ahn
Department of Neurology, Seoul Medical Center, 156 Shinnae-dong, Chungrang-gu, Seoul 131-130
Korea

Background: Microbleeds (MBs) are observed frequently in Alzheimer«SQ»s disease (AD) and suggested to play a crucial role in the pathophysiology, but their clinical significance remains unclear. Materials and Methods: The study recruited 100 patients with AD who were diagnosed at the memory clinic in Seoul Medical Center in 2014. For each patient, baseline characteristics, neuropsychological tests, cerebrovascular risk factors, medial temporal lobe atrophy (MTLA), and severity of small vessel disease (SVD) according to the existence of MBs were evaluated. Results: The prevalence of MBs in patients with AD was 33%. The percentage of male gender, the severity of SVD and MTLA were significantly increased in MB(+) group. The MB(+) group showed more severe MTLA and SVD than MB(−) group. Conclusions: These results suggested that MBs might reflect the burden of amyloid and ischemic vascular pathology.


How to cite this article:
Heo JH, Im DG, Lee SH, Ahn JY. The clinical significance of brain microbleeds in patients with Alzheimer's disease: Preliminary study.Ann Indian Acad Neurol 2016;19:495-498


How to cite this URL:
Heo JH, Im DG, Lee SH, Ahn JY. The clinical significance of brain microbleeds in patients with Alzheimer's disease: Preliminary study. Ann Indian Acad Neurol [serial online] 2016 [cited 2022 Aug 20 ];19:495-498
Available from: https://www.annalsofian.org/article.asp?issn=0972-2327;year=2016;volume=19;issue=4;spage=495;epage=498;aulast=Heo;type=0