Annals of Indian Academy of Neurology
ORIGINAL ARTICLE
Year
: 2022  |  Volume : 25  |  Issue : 3  |  Page : 449--456

Cross-sectional area reference values of nerves in the upper and lower extremities using ultrasonography in the Indian population


DM Sindhu1, Akshata Huddar1, Jitender Saini2, Seena Vengalil1, Saraswati Nashi1, Mainak Bardhan3, Gopikrishnan Unnikrishnan1, Rahul Reddy Rajula1, Thennarasu Kandavel4, Lokesh Bathala5, Leo H Visser6, Atchayaram Nalini1 
1 Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India
2 Department of Neuro Imaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India
3 Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka; ICMR-National Institute of Cholera and Enteric Diseases (NICED), Kolkata, West Bengal, India
4 Department of Biostatistics, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India
5 Department of Neurology, Aster CMI Hospital, Bangalore, Karnataka, India
6 Department of Neurology and Clinical Neurophysiology, ETZ, St. Elisabeth Hospital, Tilburg, Netherlands

Correspondence Address:
Atchayaram Nalini
Department of Neurology, National Institute of Mental Health and Neurosciences, Hosur Road, Bengaluru - 560 029, Karnataka
India

Background and Purpose: Cross-sectional area (CSA) is the most important parameter to study peripheral nerves by high-resolution ultrasonography. The aim was to acquire normative data of CSA of the main upper and lower limb nerves in the Indian population. Methods: CSA of nerves was determined in 100 healthy volunteers at 11 predetermined sites: median and ulnar at the wrist, mid-forearm, elbow; radial (spiral groove); tibial (popliteal fossa, medial malleolus); common peroneal (CPN, fibular head) and sural (lateral malleolus). Results: The mean age of participants was 40.7 ± 13.0 years (range: 18-79). Fifty were < 40 years of age. The mean height, weight and BMI were 161.5 ± 8.3 centimeters (range: 145—179), 58.6 ± 10.1 kilograms (range: 32-90) and 22.4 ± 3.2 kilogram/square meter (range: 14.03-30.44), respectively. The median and ulnar nerve measurements were non-uniform throughout its course, and the CSA was largest at the elbow and ulnar groove, respectively. With advancing age, there was a significant difference for median and ulnar nerves at the wrist (median P = 0.002, ulnar P = 0.009) and tibial nerve (popliteal fossa, P = 0.045, medial malleolus, P = 0.005), CPN (P = 0.047). Men had greater CSA of upper limb nerves and tibial nerves at popliteal fossa (P < 0.05) as compared to women. A positive correlation was noted with weight. Conclusion: It is apt for every defined population to have its own set of normative data of CSA as it varies with ethnicity, age, and the built of individuals. We provide a valuable set of CSA data for nerves in the Indian population, which can be used for comparison while investigating peripheral nerve disorders.


How to cite this article:
Sindhu D M, Huddar A, Saini J, Vengalil S, Nashi S, Bardhan M, Unnikrishnan G, Rajula RR, Kandavel T, Bathala L, Visser LH, Nalini A. Cross-sectional area reference values of nerves in the upper and lower extremities using ultrasonography in the Indian population.Ann Indian Acad Neurol 2022;25:449-456


How to cite this URL:
Sindhu D M, Huddar A, Saini J, Vengalil S, Nashi S, Bardhan M, Unnikrishnan G, Rajula RR, Kandavel T, Bathala L, Visser LH, Nalini A. Cross-sectional area reference values of nerves in the upper and lower extremities using ultrasonography in the Indian population. Ann Indian Acad Neurol [serial online] 2022 [cited 2022 Oct 5 ];25:449-456
Available from: https://www.annalsofian.org/article.asp?issn=0972-2327;year=2022;volume=25;issue=3;spage=449;epage=456;aulast=Sindhu;type=0