Annals of Indian Academy of Neurology
: 2022  |  Volume : 25  |  Issue : 3  |  Page : 511-

Cerebral Malaria, COVID-19 and complete blood examination

Rujittika Mungmunpuntipantip1, Viroj Wiwanitkit2,  
1 Private Academic Consultant, Bangkok, Thailand
2 Department of Community Medicine, Dr. DY Patil University, Pune, Maharashtra, India

Correspondence Address:
Rujittika Mungmunpuntipantip
Private Academic Consultant, Bangkok

How to cite this article:
Mungmunpuntipantip R, Wiwanitkit V. Cerebral Malaria, COVID-19 and complete blood examination.Ann Indian Acad Neurol 2022;25:511-511

How to cite this URL:
Mungmunpuntipantip R, Wiwanitkit V. Cerebral Malaria, COVID-19 and complete blood examination. Ann Indian Acad Neurol [serial online] 2022 [cited 2022 Oct 7 ];25:511-511
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Dear Editor,

We read the report by Ram et al.[1] with great interest. Ram et al.[1] reported on the co-occurrence of COVID-19 and malaria and concluded that “Every suspected case of COVID encephalitis has to be investigated for all possible causes …….” In the present report, it is likely that there is a problem in the first complete blood count examination. In laboratory medicine, a blood smear examination should be routinely done, and it is usually neglected when an automated hematology analyzer is widely used. Because the incubation period for COVID-19 (14 days) and cerebral malaria (12 days) can overlap, it is no doubt that there might be a co-infection and a disease might be underdiagnosed.[2] Also, it is possible that malaria might be a recurrence, not a newly acquired infection, and co-manifest with COVID-19.[3] When hydroxychloroquine is used for the management of COVID-19, it might also manage malaria co-infection in some cases and co-infection might be finally underdiagnosed.

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1Ram A, Padmanabhan S, Warrier AR, Wilson A. Cerebral malaria in a patient with COVID-19. Ann Indian Acad Neurol 2021;24:616-7.
2Sardar S, Sharma R, Alyamani TYM, Aboukamar M. COVID-19 and plasmodium vivax malaria co-infection. IDCases 2020;21:e00879.
3Pusparani A, Henrina J, Cahyadi A. Co-infection of COVID-19 and recurrent malaria. J Infect Dev Ctries 2021;15:625-9.