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Figure 3: Diagnostic approach and management algorithm for limbic encephalitis HHV6 - human herpes virus 6, HSV - herpes simplex virus, VGKC - voltage gated potassium channel, NMDAR - N-methyl-D-aspartate receptor, CV2/CRMP5 - collapsin responsemediator protein 5, PET - positron emission tomography, LGI1 - leucine-rich, glioma-inactivated 1, CASPER2 - contactin associated protein 2. 1st line immunosuppression-intravenous methyl predinisolone and intravenous immunoglobulin or plasma exchange, 2nd line immunosuppression-rituximab or cyclophosphamide or both

Figure 3: Diagnostic approach and management algorithm for limbic encephalitis HHV6 - human herpes virus 6, HSV - herpes simplex virus, VGKC - voltage gated potassium channel, NMDAR - N-methyl-D-aspartate receptor, CV2/CRMP5 - collapsin responsemediator protein 5, PET - positron emission tomography, LGI1 - leucine-rich, glioma-inactivated 1, CASPER2 - contactin associated protein 2. 1st line immunosuppression-intravenous methyl predinisolone and intravenous immunoglobulin or plasma exchange, 2nd line immunosuppression-rituximab or cyclophosphamide or both