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Figure 2: Ictal high frequency oscillations (HFOs). Left panel: at conventional setting of 1.6-70 Hz and 10 s per page window, conventional seizure onset (marker CO) consisting of rhythmic beta activity is seen in the MT channels located in the inferomesial temporal region of the same patient as in Figure 1. At the time of and preceding the conventional seizure onset, the adjacent AT channels show attenuation (highlighted segment). Right panel: at high frequency setting of 53-600 Hz and 1 s per page window, prominent rhythmic ictal HFOs are seen in AT2-3 and AT3-4 channels but not in the adjacent MT channels, demonstrating temporal and spatial differences between seizure onsets defined by conventional frequency activity and HFOs. Note that the highlighted segments in the two panels correspond to each other in time

Figure 2: Ictal high frequency oscillations (HFOs). Left panel: at conventional setting of 1.6-70 Hz and 10 s per page window, conventional seizure onset (marker CO) consisting of rhythmic beta activity is seen in the MT channels located in the inferomesial temporal region of the same patient as in Figure 1. At the time of and preceding the conventional seizure onset, the adjacent AT channels show attenuation (highlighted segment). Right panel: at high frequency setting of 53-600 Hz and 1 s per page window, prominent rhythmic ictal HFOs are seen in AT2-3 and AT3-4 channels but not in the adjacent MT channels, demonstrating temporal and spatial differences between seizure onsets defined by conventional frequency activity and HFOs. Note that the highlighted segments in the two panels correspond to each other in time