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Figure 1: Merosin deficient CMD: H and E showing features of muscular dystrophy with variation in fiber size, rounding of fibers, and increased endomysial collagen (a). Complete loss of expression of laminin α2 (b), secondary reduction of laminin β1 (c), overexpression of laminin α5 (d), preserved expression of laminin γ1 (e), and collagen VI (A1,2,3) (f)

Figure 1: Merosin deficient CMD: H and E showing features of muscular dystrophy with variation in fiber size, rounding of fibers, and increased endomysial collagen (a). Complete loss of expression of laminin α2 (b), secondary reduction of laminin β1 (c), overexpression of laminin α5 (d), preserved expression of laminin γ1 (e), and collagen VI (A1,2,3) (f)